Epidemiology of Hepatocellular Carcinoma in the Asia-Pacific Region

Hepatocellular carcinoma (HCC) is the predominant primary liver cancer in many countries and is the third most common cause of cancer-related death in the Asia-Pacific region. The incidence of HCC is higher in men and in those over 40 years old. In the Asia-Pacific region, chronic hepatitis B virus...

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Bibliographic Details
Published in:Gut and liver Vol. 10; no. 3; pp. 332 - 339
Main Authors: Zhu, Ran Xu, Seto, Wai-Kay, Lai, Ching-Lung, Yuen, Man-Fung
Format: Journal Article
Language:English
Published: Korea (South) Editorial Office of Gut and Liver 23.05.2016
Gastroenterology Council for Gut and Liver
거트앤리버 소화기연관학회협의회
Subjects:
Aflatoxins - adverse effects
Age Distribution
Alcohol Drinking - adverse effects
Alcohol Drinking - epidemiology
Asia - epidemiology
carcinoma
Carcinoma, Hepatocellular - epidemiology
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - epidemiology
Female
Food Contamination - statistics & numerical data
Hepatitis B, Chronic - epidemiology
Hepatitis C, Chronic - epidemiology
hepatocellular
Humans
Incidence
liver neoplasms
Liver Neoplasms - epidemiology
Male
mortality
Oceania - epidemiology
Prevalence
Review
Risk Factors
내과학
Carcinoma, hepatocellular
Prevalence
Mortality
Liver neoplasms
Incidence
ISSN:1976-2283, 2005-1212
Online Access:Get full text
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Summary:Hepatocellular carcinoma (HCC) is the predominant primary liver cancer in many countries and is the third most common cause of cancer-related death in the Asia-Pacific region. The incidence of HCC is higher in men and in those over 40 years old. In the Asia-Pacific region, chronic hepatitis B virus and hepatitis C virus infections are the main etiological agents; in particular, chronic hepatitis B infection (CHB) is still the major cause in all Asia-Pacific countries except for Japan. Over the past two decades, the incidence of HCC has remained stable in countries in the region except for Singapore and Hong Kong, where the incidence for both sexes is currently decreasing. Chronic hepatitis C infection (CHC) is an important cause of HCC in Japan, representing 70% of HCCs. Over the past several decades, the prevalence of CHC has been increasing in many Asia-Pacific countries, including Australia, New Zealand, and India. Despite advancements in treatment, HCC is still an important health problem because of the associated substantial mortality. An effective surveillance program could offer early diagnosis and hence better treatment options. Antiviral treatment for both CHB and CHC is effective in reducing the incidence of HCC.
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G704-SER000001589.2016.10.3.007
ISSN:1976-2283
2005-1212
DOI:10.5009/gnl15257