Epidemiology of Hepatocellular Carcinoma in the Asia-Pacific Region

Hepatocellular carcinoma (HCC) is the predominant primary liver cancer in many countries and is the third most common cause of cancer-related death in the Asia-Pacific region. The incidence of HCC is higher in men and in those over 40 years old. In the Asia-Pacific region, chronic hepatitis B virus...

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Veröffentlicht in:	Gut and liver Jg. 10; H. 3; S. 332 - 339
Hauptverfasser:	Zhu, Ran Xu, Seto, Wai-Kay, Lai, Ching-Lung, Yuen, Man-Fung
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Korea (South) Editorial Office of Gut and Liver 23.05.2016 Gastroenterology Council for Gut and Liver 거트앤리버 소화기연관학회협의회
Schlagworte:	Aflatoxins - adverse effects Age Distribution Alcohol Drinking - adverse effects Alcohol Drinking - epidemiology Asia - epidemiology carcinoma Carcinoma, Hepatocellular - epidemiology Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - epidemiology Female Food Contamination - statistics & numerical data Hepatitis B, Chronic - epidemiology Hepatitis C, Chronic - epidemiology hepatocellular Humans Incidence liver neoplasms Liver Neoplasms - epidemiology Male mortality Oceania - epidemiology Prevalence Review Risk Factors 내과학 Carcinoma, hepatocellular Prevalence Mortality Liver neoplasms Incidence
ISSN:	1976-2283, 2005-1212
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Abstract	Hepatocellular carcinoma (HCC) is the predominant primary liver cancer in many countries and is the third most common cause of cancer-related death in the Asia-Pacific region. The incidence of HCC is higher in men and in those over 40 years old. In the Asia-Pacific region, chronic hepatitis B virus and hepatitis C virus infections are the main etiological agents; in particular, chronic hepatitis B infection (CHB) is still the major cause in all Asia-Pacific countries except for Japan. Over the past two decades, the incidence of HCC has remained stable in countries in the region except for Singapore and Hong Kong, where the incidence for both sexes is currently decreasing. Chronic hepatitis C infection (CHC) is an important cause of HCC in Japan, representing 70% of HCCs. Over the past several decades, the prevalence of CHC has been increasing in many Asia-Pacific countries, including Australia, New Zealand, and India. Despite advancements in treatment, HCC is still an important health problem because of the associated substantial mortality. An effective surveillance program could offer early diagnosis and hence better treatment options. Antiviral treatment for both CHB and CHC is effective in reducing the incidence of HCC.
AbstractList	Hepatocellular carcinoma (HCC) is the predominant primary liver cancer in many countries and is the third most common cause of cancer-related death in the Asia-Pacific region. The incidence of HCC is higher in men and in those over 40 years old. In the Asia-Pacific region, chronic hepatitis B virus and hepatitis C virus infections are the main etiological agents; in particular, chronic hepatitis B infection (CHB) is still the major cause in all Asia-Pacific countries except for Japan. Over the past two decades, the incidence of HCC has remained stable in countries in the region except for Singapore and Hong Kong, where the incidence for both sexes is currently decreasing. Chronic hepatitis C infection (CHC) is an important cause of HCC in Japan, representing 70% of HCCs. Over the past several decades, the prevalence of CHC has been increasing in many Asia-Pacific countries, including Australia, New Zealand, and India. Despite advancements in treatment, HCC is still an important health problem because of the associated substantial mortality. An effective surveillance program could offer early diagnosis and hence better treatment options. Antiviral treatment for both CHB and CHC is effective in reducing the incidence of HCC. Hepatocellular carcinoma (HCC) is the predominant primary liver cancer in many countries and is the third most common cause of cancer-related death in the Asia-Pacific region. The incidence of HCC is higher in men and in those over 40 years old. In the Asia-Pacific region, chronic hepatitis B virus and hepatitis C virus infections are the main etiological agents; in particular, chronic hepatitis B infection (CHB) is still the major cause in all Asia-Pacific countries except for Japan. Over the past two decades, the incidence of HCC has remained stable in countries in the region except for Singapore and Hong Kong, where the incidence for both sexes is currently decreasing. Chronic hepatitis C infection (CHC) is an important cause of HCC in Japan, representing 70% of HCCs. Over the past several decades, the prevalence of CHC has been increasing in many Asia-Pacific countries, including Australia, New Zealand, and India. Despite advancements in treatment, HCC is still an important health problem because of the associated substantial mortality. An effective surveillance program could offer early diagnosis and hence better treatment options. Antiviral treatment for both CHB and CHC is effective in reducing the incidence of HCC. KCI Citation Count: 166
Author	Seto, Wai-Kay Yuen, Man-Fung Lai, Ching-Lung Zhu, Ran Xu
AuthorAffiliation	Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
AuthorAffiliation_xml	– name: Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China – name: Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China
Author_xml	– sequence: 1 givenname: Ran Xu surname: Zhu fullname: Zhu, Ran Xu organization: Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China – sequence: 2 givenname: Wai-Kay surname: Seto fullname: Seto, Wai-Kay organization: Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China – sequence: 3 givenname: Ching-Lung surname: Lai fullname: Lai, Ching-Lung organization: Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China – sequence: 4 givenname: Man-Fung surname: Yuen fullname: Yuen, Man-Fung organization: Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/27114433$$D View this record in MEDLINE/PubMed https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002107693$$DAccess content in National Research Foundation of Korea (NRF)
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Copyright	Copyright © 2016 by The Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer. 2016
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SubjectTerms	Aflatoxins - adverse effects Age Distribution Alcohol Drinking - adverse effects Alcohol Drinking - epidemiology Asia - epidemiology carcinoma Carcinoma, Hepatocellular - epidemiology Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - epidemiology Female Food Contamination - statistics & numerical data Hepatitis B, Chronic - epidemiology Hepatitis C, Chronic - epidemiology hepatocellular Humans Incidence liver neoplasms Liver Neoplasms - epidemiology Male mortality Oceania - epidemiology Prevalence Review Risk Factors 내과학
Title	Epidemiology of Hepatocellular Carcinoma in the Asia-Pacific Region
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