Sub-threshold panic attacks and agoraphobic avoidance increase comorbidity of mental disorders: Results from an adult general population sample

•We investigated persons with isolated panic attacks (PA) and panic disorder (PD).•For the first time limited symptom attacks (LSA) were included in analyses.•All panic attack subtypes were associated with frequent comorbidity.•Odds for comorbidity increased from LSA to PA to PD.•The presence of ago...

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Vydáno v:Journal of anxiety disorders Ročník 27; číslo 5; s. 485 - 493
Hlavní autoři: Pané-Farré, Christiane A., Fenske, Kristin, Stender, Jan P., Meyer, Christian, John, Ulrich, Rumpf, Hans-Jürgen, Hapke, Ulfert, Hamm, Alfons O.
Médium: Journal Article
Jazyk:angličtina
Vydáno: Amsterdam Elsevier Ltd 01.06.2013
Elsevier
Témata:
Adolescent
Adult
Adult and adolescent clinical studies
Agoraphobia
Agoraphobia - epidemiology
Agoraphobia - psychology
Anxiety disorders. Neuroses
Avoidance
Biological and medical sciences
Clinical practice
Comorbidity
Diagnostic and Statistical Manual of Mental Disorders
Diagnostic testing
Epidemiology
Female
General aspects
Humans
Limited symptom attack
Male
Medical sciences
Middle Aged
Panic
Panic attack
Panic disorder
Panic Disorder - epidemiology
Panic Disorder - psychology
Panic disorders
Psychiatric disorders
Psychiatry
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Symptoms
Young Adult
Limited symptom attack
Comorbidity
Epidemiology
Panic attack
Panic disorder
Human
Concomitant disease
Agoraphobia
Anxiety disorder
Mental disorder
Adult
Avoidance
ISSN:0887-6185, 1873-7897, 1873-7897
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Shrnutí:•We investigated persons with isolated panic attacks (PA) and panic disorder (PD).•For the first time limited symptom attacks (LSA) were included in analyses.•All panic attack subtypes were associated with frequent comorbidity.•Odds for comorbidity increased from LSA to PA to PD.•The presence of agoraphobia increased comorbidity rates. Full-blown panic attacks are frequently associated with other mental disorders. Most comorbidity analyses did not discriminate between isolated panic attacks vs. panic attacks that occurred in the context of a panic disorder and rarely evaluated the impact of comorbid agoraphobia. Moreover, there are no larger scale epidemiological studies regarding the influence of sub-threshold panic attacks. 4075 German-speaking respondents aged 18–64 were interviewed using the fully structured Munich Composite International Diagnostic Interview. Limited symptom attacks, isolated panic attacks, and panic disorder were associated with other lifetime DSM-IV disorders with monotonically increasing odds and increasing tendency for multiple comorbidities across the three groups. The presence of agoraphobia was associated with more frequent comorbidity in all panic subgroups and also in persons who never experienced panic attacks. The present study suggests that populations with isolated or limited symptom should be carefully attended to in clinical practice, especially if agoraphobia is present.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0887-6185
1873-7897
1873-7897
DOI:10.1016/j.janxdis.2013.06.008