The macrophage: a key player in the pathophysiology of peripheral neuropathies

Macrophages are present in all mammalian tissues and coexist with various cell types in order to respond to different environmental cues. However, the role of these cells has been underestimated in the context of peripheral nerve damage. More importantly, macrophages display divergent characteristic...

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Bibliographic Details
Published in:	Journal of neuroinflammation Vol. 19; no. 1; pp. 97 - 18
Main Authors:	Msheik, Zeina, El Massry, Mohamed, Rovini, Amandine, Billet, Fabrice, Desmoulière, Alexis
Format:	Journal Article
Language:	English
Published:	London BioMed Central 16.04.2022 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Animals Biomedical and Life Sciences Biomedicine Bone marrow Cell activation Cell fate Development and progression Divergence Fate maps Genotype & phenotype Growth factors Health aspects Homeostasis Immunology Inflammation Insects Macrophage polarization Macrophages Macrophages - pathology Mammals Metabolism Microenvironments Nerve-resident macrophages Nervous system Neurobiology Neurodegeneration Neuroinflammation Neurology Neurosciences Ontogeny Oxidative stress Peripheral Nerve Injuries - pathology Peripheral nerves Peripheral Nerves - pathology Peripheral neuropathy Physiological aspects Physiology Polyneuropathies Reactive oxygen species Review Risk factors Schwann Cells - pathology Transcriptomics Wallerian degeneration Wallerian Degeneration - pathology France Oxidative stress Neuroinflammation Macrophage polarization Wallerian degeneration Peripheral neuropathy Nerve-resident macrophages
ISSN:	1742-2094, 1742-2094
Online Access:	Get full text
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