Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers

For this study, new dendrimers were prepared from poly(propylene imine) (PPI) and polyamidoamine (PAMAM) dendrimers using an efficient acid-base reaction with various phenolic acids. The syntheses were also optimized in both microwave and microfluidic reactors. These ionic and hydrophilic dendrimers...

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Bibliographic Details
Published in:Polymers Vol. 14; no. 17; p. 3513
Main Authors: Bacha, Katia, Estager, Julien, Brassart-Pasco, Sylvie, Chemotti, Catherine, Fernandes, Antony E., Mbakidi, Jean-Pierre, Deleu, Magali, Bouquillon, Sandrine
Format: Journal Article
Language:English
Published: Basel MDPI AG 27.08.2022
MDPI
Subjects:
Acid-base reactions
Acids
antioxidant
Antioxidants
Biochemistry, biophysics & molecular biology
Biochimie, biophysique & biologie moléculaire
Cancer
Chemical Sciences
Chemistry (all)
Cosmetics
Dendrimers
Ethanol
flow chemistry
Functionalized
Gastrointestinal agents
General Chemistry
Life sciences
Micro-fluidic reactors
Microfluidics
microwave
Microwave reactors
Nanoparticles
PAMAM dendrimer
Phenolic acids
Poly (propylene imine) dendrimers
Polyamidoamine dendrimers
Polymer blends
Polymers
Polymers and Plastics
Polyphenols
Polypropyleneimine
PPI dendrimers
Sciences du vivant
France
antioxidant
dendrimers
microwave
phenolic acids
flow chemistry
ISSN:2073-4360, 2073-4360
Online Access:Get full text
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Summary:For this study, new dendrimers were prepared from poly(propylene imine) (PPI) and polyamidoamine (PAMAM) dendrimers using an efficient acid-base reaction with various phenolic acids. The syntheses were also optimized in both microwave and microfluidic reactors. These ionic and hydrophilic dendrimers were fully characterized and showed excellent antioxidant properties. Their cytotoxic properties have been also determined in the case of fibroblast dermal cells.
Bibliography:ObjectType-Article-1
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scopus-id:2-s2.0-85137752430
ISSN:2073-4360
2073-4360
DOI:10.3390/polym14173513