Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS‐CoV‐2

From the beginning of 2002 and 2012, severe respiratory syndrome coronavirus (SARS‐CoV) and Middle East respiratory syndrome coronavirus (MERS‐CoV) crossed the species barriers to infect humans, causing thousands of infections and hundreds of deaths, respectively. Currently, a novel coronavirus (SAR...

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Bibliographic Details
Published in:	Journal of medical virology Vol. 92; no. 6; pp. 595 - 601
Main Authors:	Liu, Zhixin, Xiao, Xiao, Wei, Xiuli, Li, Jian, Yang, Jing, Tan, Huabing, Zhu, Jianyong, Zhang, Qiwei, Wu, Jianguo, Liu, Long
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.06.2020 John Wiley and Sons Inc
Subjects:	ACE2 Amino Acid Sequence Amino acids Angiotensin Angiotensin-Converting Enzyme 2 angiotensin‐converting enzyme 2 (ACE2) Animals Aquatic reptiles Betacoronavirus - classification Betacoronavirus - genetics Betacoronavirus - pathogenicity Binding Binding Sites Chelonia mydas China - epidemiology Chiroptera - virology Coronaviridae Coronavirus Disease 2019 (COVID‐19) Coronavirus Infections - epidemiology Coronavirus Infections - transmission Coronavirus Infections - virology Coronaviruses COVID-19 Disease transmission Divergence Epidemics Eutheria - virology Fatalities Humans Models, Molecular Pandemics Pelodiscus sinensis Peptidyl-Dipeptidase A - chemistry Peptidyl-Dipeptidase A - genetics Peptidyl-Dipeptidase A - metabolism Phylogeny Pneumonia, Viral - epidemiology Pneumonia, Viral - transmission Pneumonia, Viral - virology Protein Binding Protein Conformation, alpha-Helical Protein Conformation, beta-Strand Protein Interaction Domains and Motifs Protein Interaction Mapping Proteins Receptors Receptors, Virus - chemistry Receptors, Virus - genetics Receptors, Virus - metabolism receptor‐binding domain (RBD) of coronavirus Respiratory diseases SARS-CoV-2 SARS‐CoV‐2 spike protein (S) Sequence Alignment Sequence Homology, Amino Acid Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Snakes - virology Spike Glycoprotein, Coronavirus - chemistry Spike Glycoprotein, Coronavirus - classification Spike Glycoprotein, Coronavirus - genetics Spike Glycoprotein, Coronavirus - metabolism Spike protein Transmission Turtles Turtles - virology Viral diseases Virology China angiotensin-converting enzyme 2 (ACE2) SARS-CoV-2 Coronavirus Disease 2019 (COVID-19) SARS-CoV-2 spike protein (S) receptor-binding domain (RBD) of coronavirus
ISSN:	0146-6615, 1096-9071, 1096-9071
Online Access:	Get full text
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