Multiple roles of caspase‐8 in cell death, inflammation, and innate immunity

Caspase‐8 is an apical caspase involved in the programmed form of cell death called apoptosis that is critically important for mammalian development and immunity. Apoptosis was historically described as immunologically silent in contrast to other types of programmed cell death such as necroptosis or...

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Bibliographic Details
Published in:	Journal of leukocyte biology Vol. 109; no. 1; pp. 121 - 141
Main Authors:	Orning, Pontus, Lien, Egil
Format:	Journal Article
Language:	English
Published:	United States Oxford University Press 01.01.2021
Subjects:	Animals Apoptosis caspase Caspase 8 - immunology Caspase-8 Cell death Cell Death - immunology Humans Immune response Immunity, Innate - immunology Inflammasomes Inflammation Inflammation - immunology Innate immunity Kinases Microorganisms Mortality Necroptosis Pyroptosis TNF pyroptosis apoptosis inflammasomes TNF caspase necroptosis
ISSN:	0741-5400, 1938-3673, 1938-3673
Online Access:	Get full text
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