Multiple loci with different cancer specificities within the 8q24 gene desert

Recent studies based on genome-wide association, linkage, and admixture scan analysis have reported associations of various genetic variants in 8q24 with susceptibility to breast, prostate, and colorectal cancer. This locus lies within a 1.18-Mb region that contains no known genes but is bounded at...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute Jg. 100; H. 13; S. 962
Hauptverfasser:	Ghoussaini, Maya, Song, Honglin, Koessler, Thibaud, Al Olama, Ali Amin, Kote-Jarai, Zsofia, Driver, Kristy E, Pooley, Karen A, Ramus, Susan J, Kjaer, Susanne Krüger, Hogdall, Estrid, DiCioccio, Richard A, Whittemore, Alice S, Gayther, Simon A, Giles, Graham G, Guy, Michelle, Edwards, Stephen M, Morrison, Jonathan, Donovan, Jenny L, Hamdy, Freddie C, Dearnaley, David P, Ardern-Jones, Audrey T, Hall, Amanda L, O'Brien, Lynne T, Gehr-Swain, Beatrice N, Wilkinson, Rosemary A, Brown, Paul M, Hopper, John L, Neal, David E, Pharoah, Paul D P, Ponder, Bruce A J, Eeles, Rosalind A, Easton, Douglas F, Dunning, Alison M
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 02.07.2008
Schlagworte:	Adult Aged Breast Neoplasms - genetics Case-Control Studies Chromosome Mapping Chromosomes, Human, Pair 8 - genetics Colorectal Neoplasms - genetics Female Gene Frequency Genetic Predisposition to Disease Genotype Haplotypes Humans Logistic Models Male Middle Aged Ovarian Neoplasms - genetics Polymorphism, Single Nucleotide Prostatic Neoplasms - genetics
ISSN:	1460-2105, 1460-2105
Online-Zugang:	Weitere Angaben
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