Complexity and algorithms for copy-number evolution problems

Background Cancer is an evolutionary process characterized by the accumulation of somatic mutations in a population of cells that form a tumor. One frequent type of mutations is copy number aberrations, which alter the number of copies of genomic regions. The number of copies of each position along...

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Veröffentlicht in:	Algorithms for molecular biology Jg. 12; H. 1; S. 13 - 11
Hauptverfasser:	El-Kebir, Mohammed, Raphael, Benjamin J., Shamir, Ron, Sharan, Roded, Zaccaria, Simone, Zehavi, Meirav, Zeira, Ron
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 16.05.2017 Springer Nature B.V BMC
Schlagworte:	Aberration Algorithms Bioinformatics Biomedical and Life Sciences Cancer Cellular and Medical Topics Children Chromosomes Complexity Computational Biology/Bioinformatics Computer simulation Computing time Copy number Copy-number variant Diagnosis Dynamic programming Evolutionary algorithms Genes Graph theory Leaves Life Sciences Maximum parsimony Mutation Phylogenetics Phylogeny Physiological Prognosis Quality assessment Selected papers from WABI 2016 Somatic mutation Somatic mutation Phylogeny Maximum parsimony Copy-number variant Cancer
ISSN:	1748-7188, 1748-7188
Online-Zugang:	Volltext
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