Effectiveness of sustained leisure-time physical activity strategies for obesity-related cancer prevention: an emulated target trial in a prospective US cohort

Background Obesity-related cancers account for 40% of US cancer cases, and their global burden continues to rise. Cancer prevention guidelines recommend 150–300 min of moderate or 75–150 min of vigorous-intensity activity per week (7.5–15 MET-hrs/wk). However, the long-term causal effect of sustaine...

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Bibliographic Details
Published in:	BMC medicine Vol. 23; no. 1; pp. 580 - 16
Main Authors:	Elahy, Valeria, Chiu, Yu-Han, Patel, Alpa V., Rees-Punia, Erika, McCullough, Marjorie L., Peoples, Anita R., Wang, Ying
Format:	Journal Article
Language:	English
Published:	London BioMed Central 27.10.2025 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Adult Aerobics Aged Analysis Biomedicine Cancer Cancer prevention Care and treatment Chronic diseases Clinical trials Complications and side effects Disease prevention Exercise Female Health aspects Health risks Humans Intervention Leisure Leisure Activities Leisure-time physical activity Lifestyles Male Medical diagnosis Medical research Medicine Medicine & Public Health Metabolism Middle Aged Neoplasms - epidemiology Neoplasms - etiology Neoplasms - prevention & control Nutrition research Obesity Obesity - complications Obesity-related cancers Oncology, Experimental Parametric g-formula Physical activity Physical fitness Prevention Prospective Studies Questionnaires Risk factors Risk management Risk reduction Target trial emulation United States - epidemiology United States United States > US Causal inference Parametric g-formula Physical activity ACS guidelines Chronic disease prevention Obesity-related cancers Cancer prevention Target trial emulation Older adults Leisure-time physical activity
ISSN:	1741-7015, 1741-7015
Online Access:	Get full text
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