Solving the master equation for Indels

Background Despite the long-anticipated possibility of putting sequence alignment on the same footing as statistical phylogenetics, theorists have struggled to develop time-dependent evolutionary models for indels that are as tractable as the analogous models for substitution events. Main text This...

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Bibliographic Details
Published in:	BMC bioinformatics Vol. 18; no. 1; pp. 255 - 10
Main Author:	Holmes, Ian H.
Format:	Journal Article
Language:	English
Published:	London BioMed Central 12.05.2017 Springer Nature B.V BMC
Subjects:	Algorithms Alignment Bioinformatics Biomedical and Life Sciences Commentary Computational Biology/Bioinformatics Computer Appl. in Life Sciences Computer Simulation Evolution INDEL Mutation - genetics Indels Insertion Life Sciences Markov analysis Markov Chains Mathematical analysis Mathematical models Microarrays Models, Theoretical Monte Carlo Method Nucleotide sequence Pathogens Phylogenetics Phylogeny Probability distribution Proteins Sequence Alignment Sequence analysis (methods) State machines Statistical analysis Statistics Time dependence Transducers Phylogenetics Alignment Indels
ISSN:	1471-2105, 1471-2105
Online Access:	Get full text
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