Multistability in the epithelial-mesenchymal transition network

Background The transitions between epithelial (E) and mesenchymal (M) cell phenotypes are essential in many biological processes like tissue development and cancer metastasis. Previous studies, both modeling and experimental, suggested that in addition to E and M states, the network responsible for...

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Bibliographic Details
Published in:	BMC bioinformatics Vol. 21; no. 1; pp. 71 - 17
Main Authors:	Xin, Ying, Cummins, Bree, Gedeon, Tomáš
Format:	Journal Article
Language:	English
Published:	London BioMed Central 24.02.2020 Springer Nature B.V BMC
Subjects:	Algorithms Analysis and modelling of complex systems Bioinformatics Biomarkers Biomedical and Life Sciences Boolean Cancer Cell adhesion & migration Complex systems Computational Biology/Bioinformatics Computer Appl. in Life Sciences Epithelial-Mesenchymal Transition Genotype & phenotype Life Sciences Medical prognosis Mesenchyme Metastasis Microarrays Models, Biological Motility Multistability Network models Phenotype Research Article Software Epithelial-mesenchymal transition Multistability Network models
ISSN:	1471-2105, 1471-2105
Online Access:	Get full text
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