Signaling networks in immunometabolism

Adaptive immunity is essential for pathogen and tumor eradication, but may also trigger uncontrolled or pathological inflammation. T cell receptor, co-stimulatory and cytokine signals coordinately dictate specific signaling networks that trigger the activation and functional programming of T cells....

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Veröffentlicht in:	Cell research Jg. 30; H. 4; S. 328 - 342
Hauptverfasser:	Saravia, Jordy, Raynor, Jana L., Chapman, Nicole M., Lim, Seon Ah, Chi, Hongbo
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Singapore Springer Singapore 01.04.2020 Nature Publishing Group
Schlagworte:	1-Phosphatidylinositol 3-kinase 631/250/262 631/250/38 64 96 96/31 Adaptive immunity AMP-Activated Protein Kinase Kinases AMP-Activated Protein Kinases - immunology Animals Biomedical and Life Sciences Cell Biology Cytokines Effectors Functional programming Humans Immunology Kinases Life Sciences LKB1 protein Lymphocytes Lymphocytes T Metabolism Networks Phosphatidylinositol 3-Kinases - immunology Protein Serine-Threonine Kinases - immunology Protein-serine/threonine kinase Regulators Review Review Article Signal Transduction Signaling T cell receptors T-Lymphocytes - immunology T-Lymphocytes - metabolism Therapeutic applications TOR protein TOR Serine-Threonine Kinases - immunology
ISSN:	1001-0602, 1748-7838, 1748-7838
Online-Zugang:	Volltext
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