Frequency and geographic distribution of TERT promoter mutations in primary hepatocellular carcinoma

Primary hepatocellular carcinoma (HCC) mainly develops in subjects chronically infected with hepatitis B (HBV) and C (HCV) viruses through a multistep process characterized by the accumulation of genetic alterations in the human genome. Nucleotide changes in coding regions (i.e. TP53, CTNNB1, ARID1A...

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Vydáno v:	Infectious agents and cancer Ročník 12; číslo 1; s. 27 - 9
Hlavní autoři:	Pezzuto, Francesca, Buonaguro, Luigi, Buonaguro, Franco M., Tornesello, Maria Lina
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London BioMed Central 19.05.2017 Springer Nature B.V BMC
Témata:	Biomedical and Life Sciences Biomedicine Brain cancer Cancer Research Carcinogenesis Cell cycle Chromosomes Clinical oncology Deoxyribonucleic acid DNA DNA methylation Elongation Environmental factors Etiology Gene expression Genomes Geographical distribution HCV and Cancer series Hepatitis Hepatitis B Hepatitis B virus Hepatitis C virus Hepatocellular carcinoma Infections Infectious Diseases Literature reviews Liver cancer Liver diseases Mutation Mutation hot spots Mutation rates Oncology p53 Protein Pathogenesis Review Telomerase TERT promoter mutations Tropical Medicine Tumors United States > US Europe TERT promoter mutations Hepatocellular carcinoma Hepatitis B virus Hepatitis C virus Telomerase
ISSN:	1750-9378, 1750-9378
On-line přístup:	Získat plný text
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