Current Methods for Automated Filtering of Multiple Sequence Alignments Frequently Worsen Single-Gene Phylogenetic Inference

Abstract Phylogenetic inference is generally performed on the basis of multiple sequence alignments (MSA). Because errors in an alignment can lead to errors in tree estimation, there is a strong interest in identifying and removing unreliable parts of the alignment. In recent years several automated...

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Bibliographic Details

Published in:	Systematic biology Vol. 64; no. 5; pp. 778 - 791
Main Authors:	Tan, Ge, Muffato, Matthieu, Ledergerber, Christian, Herrero, Javier, Goldman, Nick, Gil, Manuel, Dessimoz, Christophe
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01.09.2015
Subjects:	Algorithms Classification - methods Genome - genetics Phylogeny Reproducibility of Results Sequence Alignment phylogenetic inference alignment trimming alignment filtering molecular phylogeny multiple sequence alignment phylogeny phylogenetics
ISSN:	1063-5157, 1076-836X, 1076-836X
Online Access:	Get full text
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