Structure of the receptor-activated human TRPC6 and TRPC3 ion channels

TRPC6 and TRPC3 are receptor-activated nonselective cation channels that belong to the family of canonical transient receptor potential (TRPC) channels. They are activated by diacylglycerol, a lipid second messenger. TRPC6 and TRPC3 are involved in many physiological processes and implicated in huma...

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Bibliographic Details
Published in:	Cell research Vol. 28; no. 7; pp. 746 - 755
Main Authors:	Tang, Qinglin, Guo, Wenjun, Zheng, Li, Wu, Jing-Xiang, Liu, Meng, Zhou, Xindi, Zhang, Xiaolin, Chen, Lei
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.07.2018 Nature Publishing Group
Subjects:	101/28 631/535/1258/1259 631/80/313/2380 9/74 Affinity Ankyrins Biomedical and Life Sciences Cell Biology Channel opening Diglycerides Electron microscopy Inhibitors Ion channels Ions Life Sciences Molecular chains Transient receptor potential proteins
ISSN:	1001-0602, 1748-7838, 1748-7838
Online Access:	Get full text
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