Modeling Parkinson’s disease in midbrain-like organoids

Modeling Parkinson’s disease (PD) using advanced experimental in vitro models is a powerful tool to study disease mechanisms and to elucidate unexplored aspects of this neurodegenerative disorder. Here, we demonstrate that three-dimensional (3D) differentiation of expandable midbrain floor plate neu...

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Bibliographic Details
Published in:NPJ Parkinson's Disease Vol. 5; no. 1; p. 5
Main Authors: Smits, Lisa M., Reinhardt, Lydia, Reinhardt, Peter, Glatza, Michael, Monzel, Anna S., Stanslowsky, Nancy, Rosato-Siri, Marcelo D., Zanon, Alessandra, Antony, Paul M., Bellmann, Jessica, Nicklas, Sarah M., Hemmer, Kathrin, Qing, Xiaobing, Berger, Emanuel, Kalmbach, Norman, Ehrlich, Marc, Bolognin, Silvia, Hicks, Andrew A., Wegner, Florian, Sterneckert, Jared L., Schwamborn, Jens C.
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 05.04.2019
Nature Publishing Group
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ISSN:2373-8057, 2373-8057
Online Access:Get full text
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