Evaluation of cholesterol lowering treatment of patients with familial hypercholesterolemia: a large cross-sectional study in The Netherlands

Heterozygous familial hypercholesterolemia (heFH) is a common autosomal dominant hereditary disorder caused by mutations in the LDL-receptor gene that lead to elevated plasma levels of low-density lipoprotein-cholesterol (LDL-c). Robust lowering of LDL-c levels is essential for risk reduction of pre...

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Bibliographic Details
Published in:	Atherosclerosis Vol. 209; no. 1; pp. 189 - 194
Main Authors:	Pijlman, A.H., Huijgen, R., Verhagen, S.N., Imholz, B.P.M., Liem, A.H., Kastelein, J.J.P., Abbink, E.J., Stalenhoef, A.F.H., Visseren, F.L.J.
Format:	Journal Article
Language:	English
Published:	Amsterdam Elsevier Ireland Ltd 01.03.2010 Elsevier
Subjects:	Adult Aged Atherosclerosis (general aspects, experimental research) Azetidines - therapeutic use Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cardiovascular Cardiovascular Diseases - etiology Cardiovascular Diseases - prevention & control Cardiovascular system Cholesterol, LDL - blood Cross-Sectional Studies Drug Monitoring Ezetimibe Familial hypercholesterolemia Female Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Hyperlipoproteinemia Type II - blood Hyperlipoproteinemia Type II - complications Hyperlipoproteinemia Type II - drug therapy LDL-c treatment goal Lipid-lowering therapy Male Medical sciences Middle Aged Netherlands Pharmacology. Drug treatments Vasodilator agents. Cerebral vasodilators Netherlands Europe LDL-c treatment goal Lipid-lowering therapy Familial hypercholesterolemia Human Lipids Metabolic diseases Cardiovascular disease Hyperlipoproteinemia Cholesterol Genetic disease Vascular disease Lipoprotein LDL Hypercholesterolemia Treatment Atherosclerosis Dyslipemia
ISSN:	0021-9150, 1879-1484, 1879-1484
Online Access:	Get full text
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