MRI cortical thickness biomarker predicts AD-like CSF and cognitive decline in normal adults

New preclinical Alzheimer disease (AD) diagnostic criteria have been developed using biomarkers in cognitively normal (CN) adults. We implemented these criteria using an MRI biomarker previously associated with AD dementia, testing the hypothesis that individuals at high risk for preclinical AD woul...

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Bibliographische Detailangaben
Veröffentlicht in:	Neurology Jg. 78; H. 2; S. 84
Hauptverfasser:	Dickerson, Bradford C, Wolk, David A
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 10.01.2012
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - cerebrospinal fluid Alzheimer Disease - complications Alzheimer Disease - diagnosis Amyloid beta-Peptides - cerebrospinal fluid Biomarkers - cerebrospinal fluid Cerebral Cortex - pathology Cognition Disorders - cerebrospinal fluid Cognition Disorders - diagnosis Cognition Disorders - etiology Disease Progression Female Humans Magnetic Resonance Imaging Male Neuropsychological Tests Predictive Value of Tests Psychiatric Status Rating Scales Risk Factors
ISSN:	1526-632X, 1526-632X
Online-Zugang:	Weitere Angaben
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