High-dose radiotherapy with short-term or long-term androgen deprivation in localised prostate cancer (DART01/05 GICOR): a randomised, controlled, phase 3 trial

The optimum duration of androgen deprivation combined with high-dose radiotherapy in prostate cancer remains undefined. We aimed to determine whether long-term androgen deprivation was superior to short-term androgen deprivation when combined with high-dose radiotherapy. In this open-label, multicen...

Full description

Saved in:

Bibliographic Details
Published in:	The lancet oncology Vol. 16; no. 3; pp. 320 - 327
Main Authors:	Zapatero, Almudena, Guerrero, Araceli, Maldonado, Xavier, Alvarez, Ana, Segundo, Carmen Gonzalez San, Rodríguez, Maria Angeles Cabeza, Macias, Victor, Olive, Agustí Pedro, Casas, Francesc, Boladeras, Ana, de Vidales, Carmen Martín, de la Torre, Maria Luisa Vazquez, Villà, Salvador, de la Haza, Aitor Perez, Calvo, Felipe A
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.03.2015 Elsevier Limited
Subjects:	Adenocarcinoma - secondary Adenocarcinoma - therapy Aged Aged, 80 and over Androgen Antagonists - administration & dosage Androgen Antagonists - adverse effects Androgens Anilides - administration & dosage Antigens Antineoplastic Agents, Hormonal - administration & dosage Antineoplastic Agents, Hormonal - adverse effects Cancer therapies Chemoradiotherapy - adverse effects Chemoradiotherapy - methods Clinical medicine Disease-Free Survival Drug Administration Schedule Flutamide - administration & dosage Gonadotropin-Releasing Hormone - administration & dosage Hematology, Oncology and Palliative Medicine Hospitals, University Humans Intention to Treat Analysis Kaplan-Meier Estimate Male Medical research Middle Aged Neoplasm Staging Nitriles - administration & dosage Prostate cancer Prostatic Neoplasms - pathology Prostatic Neoplasms - therapy Radiation therapy Radiotherapy Dosage Radiotherapy, Conformal - adverse effects Risk Factors Spain Time Factors Tosyl Compounds - administration & dosage Treatment Outcome Spain
ISSN:	1470-2045, 1474-5488, 1474-5488
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!