A pilot trial of deferiprone for neurodegeneration with brain iron accumulation

Deferiprone was shown to reverse iron deposition in Friedreich's ataxia. This multi-center, unblinded, single-arm pilot study evaluated safety and efficacy of deferiprone for reducing cerebral iron accumulation in neurodegeneration with brain iron accumulation. Four patients with genetically-co...

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Bibliographic Details
Published in:	Haematologica (Roma) Vol. 96; no. 11; pp. 1708 - 1711
Main Authors:	Abbruzzese, G., Cossu, G., Balocco, M., Marchese, R., Murgia, D., Melis, M., Galanello, R., Barella, S., Matta, G., Ruffinengo, U., Bonuccelli, U., Forni, G. L.
Format:	Journal Article
Language:	English
Published:	Pavia Ferrata Storti Foundation 01.11.2011
Subjects:	Adult Aged Biological and medical sciences Brief Reports Female Hematologic and hematopoietic diseases Humans Iron - metabolism Iron Chelating Agents - administration & dosage Iron Chelating Agents - adverse effects Iron Metabolism Disorders - complications Iron Metabolism Disorders - diagnostic imaging Iron Metabolism Disorders - drug therapy Iron Metabolism Disorders - physiopathology Magnetic Resonance Imaging Male Medical sciences Metabolic diseases Metals (hemochromatosis...) Middle Aged Neurodegenerative Diseases - complications Neurodegenerative Diseases - diagnostic imaging Neurodegenerative Diseases - drug therapy Neurodegenerative Diseases - metabolism Other metabolic disorders Pilot Projects Pyridones - administration & dosage Pyridones - adverse effects Radiography Iron overload neurodegeneration with brain iron accumulation Hematology Central nervous system Chelating agent Metabolic diseases Clinical trial Deferiprone Iron Encephalon
ISSN:	0390-6078, 1592-8721, 1592-8721
Online Access:	Get full text
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