Inhibition of radiogenic mammary carcinoma in rats by estriol or tamoxifen

Mammary carcinomas have been induced by 3.5 Gy whole-body gamma radiation administered at age 40 to 50 days to virgin female Sprague-Dawley rats. In 142 irradiated controls carcinoma incidence averaged 7.8% in survivors observed less than 300 days and 38.3% of those surviving longer (P less than 0.0...

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Bibliographic Details

Published in:	Cancer Vol. 63; no. 9; p. 1685
Main Authors:	Lemon, H M, Kumar, P F, Peterson, C, Rodriguez-Sierra, J F, Abbo, K M
Format:	Journal Article
Language:	English
Published:	United States 01.05.1989
Subjects:	Animals Body Weight - drug effects Estriol - therapeutic use Ethinyl Estradiol - analogs & derivatives Ethinyl Estradiol - therapeutic use Female Mammary Neoplasms, Experimental - drug therapy Neoplasms, Radiation-Induced - drug therapy Organ Size - drug effects Rats Rats, Inbred Strains Tamoxifen - therapeutic use Uterus - pathology
ISSN:	0008-543X
Online Access:	Get more information
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