Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases

Beside digesting nutrients and absorbing solutes and electrolytes, the intestinal epithelium with its barrier function is in charge of a tightly controlled antigen trafficking from the intestinal lumen to the submucosa. This trafficking dictates the delicate balance between tolerance and immune resp...

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Bibliographic Details
Published in:	Tissue barriers Vol. 4; no. 4; p. e1251384
Main Authors:	Sturgeon, Craig, Fasano, Alessio
Format:	Journal Article
Language:	English
Published:	United States Taylor & Francis 01.10.2016
Subjects:	Animals autoimmune disease Autoimmune Diseases - blood Autoimmune Diseases - etiology barrier function Cholera Toxin - blood Cholera Toxin - toxicity Endothelial Cells - drug effects Endothelial Cells - metabolism Humans Inflammatory Bowel Diseases - blood Inflammatory Bowel Diseases - etiology Intestinal Mucosa - drug effects Intestinal Mucosa - metabolism intestinal permeability Reviews tight junctions Tight Junctions - drug effects Tight Junctions - metabolism zonulin intestinal permeability zonulin tight junctions autoimmune disease barrier function
ISSN:	2168-8370, 2168-8362, 2168-8370
Online Access:	Get full text
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