Clinical implication of tumor mutational burden in patients with HER2-positive refractory metastatic breast cancer

This study explored the clinical implications of tumor mutational burden (TMB) in a well-defined HER2-positive metastatic breast cancer (MBC) patient population who had been previously treated but had subsequent disease progression. Whole exome sequencing was performed on formalin-fixed paraffin-emb...

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Vydáno v:	Oncoimmunology Ročník 7; číslo 8; s. e1466768
Hlavní autoři:	Park, Song Ee, Park, Kyunghee, Lee, Eunjin, Kim, Ji-Yeon, Ahn, Jin Seok, Im, Young-Hyuck, Lee, Choonghoon, Jung, Hun, Cho, Soo Youn, Park, Woong-Yang, Cristescu, Razvan, Park, Yeon Hee
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Taylor & Francis 01.01.2018 Taylor & Francis Group
Témata:	Human epidermal growth factor receptor 2 (HER2) Long survival outcomes Metastatic breast cancer (MBC) Original Research Tumor mutational burden (TMB) whole exome sequencing (WES) Human epidermal growth factor receptor 2 (HER2) Metastatic breast cancer (MBC) Tumor mutational burden (TMB) Long survival outcomes whole exome sequencing (WES)
ISSN:	2162-402X, 2162-4011, 2162-402X
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