The Applications and Mechanisms of Superoxide Dismutase in Medicine, Food, and Cosmetics

Superoxide dismutase (SOD) is a class of enzymes that restrict the biological oxidant cluster enzyme system in the body, which can effectively respond to cellular oxidative stress, lipid metabolism, inflammation, and oxidation. Published studies have shown that SOD enzymes (SODs) could maintain a dy...

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Vydané v:Antioxidants Ročník 12; číslo 9; s. 1675
Hlavní autori: Zheng, Mengli, Liu, Yating, Zhang, Guanfeng, Yang, Zhikang, Xu, Weiwei, Chen, Qinghua
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Basel MDPI AG 27.08.2023
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ISSN:2076-3921, 2076-3921
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Abstract Superoxide dismutase (SOD) is a class of enzymes that restrict the biological oxidant cluster enzyme system in the body, which can effectively respond to cellular oxidative stress, lipid metabolism, inflammation, and oxidation. Published studies have shown that SOD enzymes (SODs) could maintain a dynamic balance between the production and scavenging of biological oxidants in the body and prevent the toxic effects of free radicals, and have been shown to be effective in anti-tumor, anti-radiation, and anti-aging studies. This research summarizes the types, biological functions, and regulatory mechanisms of SODs, as well as their applications in medicine, food production, and cosmetic production. SODs have proven to be a useful tool in fighting disease, and mimetics and conjugates that report SODs have been developed successively to improve the effectiveness of SODs. There are still obstacles to solving the membrane permeability of SODs and the persistence of enzyme action, which is still a hot spot and difficulty in mining the effect of SODs and promoting their application in the future.
AbstractList Superoxide dismutase (SOD) is a class of enzymes that restrict the biological oxidant cluster enzyme system in the body, which can effectively respond to cellular oxidative stress, lipid metabolism, inflammation, and oxidation. Published studies have shown that SOD enzymes (SODs) could maintain a dynamic balance between the production and scavenging of biological oxidants in the body and prevent the toxic effects of free radicals, and have been shown to be effective in anti-tumor, anti-radiation, and anti-aging studies. This research summarizes the types, biological functions, and regulatory mechanisms of SODs, as well as their applications in medicine, food production, and cosmetic production. SODs have proven to be a useful tool in fighting disease, and mimetics and conjugates that report SODs have been developed successively to improve the effectiveness of SODs. There are still obstacles to solving the membrane permeability of SODs and the persistence of enzyme action, which is still a hot spot and difficulty in mining the effect of SODs and promoting their application in the future.
Superoxide dismutase (SOD) is a class of enzymes that restrict the biological oxidant cluster enzyme system in the body, which can effectively respond to cellular oxidative stress, lipid metabolism, inflammation, and oxidation. Published studies have shown that SOD enzymes (SODs) could maintain a dynamic balance between the production and scavenging of biological oxidants in the body and prevent the toxic effects of free radicals, and have been shown to be effective in anti-tumor, anti-radiation, and anti-aging studies. This research summarizes the types, biological functions, and regulatory mechanisms of SODs, as well as their applications in medicine, food production, and cosmetic production. SODs have proven to be a useful tool in fighting disease, and mimetics and conjugates that report SODs have been developed successively to improve the effectiveness of SODs. There are still obstacles to solving the membrane permeability of SODs and the persistence of enzyme action, which is still a hot spot and difficulty in mining the effect of SODs and promoting their application in the future.Superoxide dismutase (SOD) is a class of enzymes that restrict the biological oxidant cluster enzyme system in the body, which can effectively respond to cellular oxidative stress, lipid metabolism, inflammation, and oxidation. Published studies have shown that SOD enzymes (SODs) could maintain a dynamic balance between the production and scavenging of biological oxidants in the body and prevent the toxic effects of free radicals, and have been shown to be effective in anti-tumor, anti-radiation, and anti-aging studies. This research summarizes the types, biological functions, and regulatory mechanisms of SODs, as well as their applications in medicine, food production, and cosmetic production. SODs have proven to be a useful tool in fighting disease, and mimetics and conjugates that report SODs have been developed successively to improve the effectiveness of SODs. There are still obstacles to solving the membrane permeability of SODs and the persistence of enzyme action, which is still a hot spot and difficulty in mining the effect of SODs and promoting their application in the future.
Audience Academic
Author Liu, Yating
Zheng, Mengli
Zhang, Guanfeng
Chen, Qinghua
Yang, Zhikang
Xu, Weiwei
AuthorAffiliation College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
AuthorAffiliation_xml – name: College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
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  givenname: Weiwei
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  givenname: Qinghua
  surname: Chen
  fullname: Chen, Qinghua
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Snippet Superoxide dismutase (SOD) is a class of enzymes that restrict the biological oxidant cluster enzyme system in the body, which can effectively respond to...
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StartPage 1675
SubjectTerms Alzheimer's disease
Amino acids
Copper
Cosmetics
Cytochrome
Cytoplasm
Enzymes
Extracellular matrix
food
food production
Free radicals
Horticultural industry
Hydrogen peroxide
inflammation
Lipid metabolism
Lipid peroxidation
medicine
Membrane permeability
Metabolism
Oxidants
Oxidation
Oxidative metabolism
Oxidative stress
Physiological aspects
Physiology
Proteins
regulating mechanism
Review
Signal transduction
Superoxide
Superoxide dismutase
Technology application
toxicity
Zinc
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Volume 12
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