Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects

Drug effects can be investigated through natural variation in the genes for their protein targets. The present study aimed to use this approach to explore the potential side effects and repurposing potential of antihypertensive drugs, which are among the most commonly used medications worldwide. Gen...

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Vydané v:	Circulation (New York, N.Y.) Ročník 140; číslo 4; s. 270
Hlavní autori:	Gill, Dipender, Georgakis, Marios K, Koskeridis, Fotios, Jiang, Lan, Feng, Qiping, Wei, Wei-Qi, Theodoratou, Evropi, Elliott, Paul, Denny, Joshua C, Malik, Rainer, Evangelou, Evangelos, Dehghan, Abbas, Dichgans, Martin, Tzoulaki, Ioanna
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 23.07.2019
Predmet:	Antihypertensive Agents - adverse effects Antihypertensive Agents - pharmacology Antihypertensive Agents - therapeutic use Drug-Related Side Effects and Adverse Reactions - genetics Humans Pharmacogenomic Variants Mendelian randomization analysis antihypertensive drugs
ISSN:	1524-4539, 1524-4539
On-line prístup:	Zistit podrobnosti o prístupe
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