Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects

Drug effects can be investigated through natural variation in the genes for their protein targets. The present study aimed to use this approach to explore the potential side effects and repurposing potential of antihypertensive drugs, which are among the most commonly used medications worldwide. Gen...

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Veröffentlicht in:	Circulation (New York, N.Y.) Jg. 140; H. 4; S. 270
Hauptverfasser:	Gill, Dipender, Georgakis, Marios K, Koskeridis, Fotios, Jiang, Lan, Feng, Qiping, Wei, Wei-Qi, Theodoratou, Evropi, Elliott, Paul, Denny, Joshua C, Malik, Rainer, Evangelou, Evangelos, Dehghan, Abbas, Dichgans, Martin, Tzoulaki, Ioanna
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 23.07.2019
Schlagworte:	Antihypertensive Agents - adverse effects Antihypertensive Agents - pharmacology Antihypertensive Agents - therapeutic use Drug-Related Side Effects and Adverse Reactions - genetics Humans Pharmacogenomic Variants Mendelian randomization analysis antihypertensive drugs
ISSN:	1524-4539, 1524-4539
Online-Zugang:	Weitere Angaben
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