mRNA Vaccines Against SARS‐CoV‐2 Variants Delivered by Lipid Nanoparticles Based on Novel Ionizable Lipids

SARS‐CoV‐2 variants are now still challenging all the approved vaccines, including mRNA vaccines. There is an urgent need to develop new generation mRNA vaccines with more powerful efficacy and better safety against SARS‐CoV‐2 variants. In this study, a new set of ionizable lipids named 4N4T are con...

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Bibliographic Details
Published in:	Advanced functional materials Vol. 32; no. 39; pp. 2204692 - n/a
Main Authors:	Chen, Kepan, Fan, Na, Huang, Hai, Jiang, Xin, Qin, Shugang, Xiao, Wen, Zheng, Qian, Zhang, Yupei, Duan, Xing, Qin, Zeyi, Liu, Yongmei, Zeng, Jun, Wei, Yuquan, Song, Xiangrong
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 01.09.2022 John Wiley and Sons Inc
Subjects:	Antibodies ionizable lipids lipid nanoparticles Lipids Lymphocytes Materials science mRNA delivery mRNA vaccines Nanoparticles Neutralizing Safety SARS‐CoV‐2 variants Severe acute respiratory syndrome coronavirus 2 Vaccines mRNA vaccines SARS‐CoV‐2 variants ionizable lipids lipid nanoparticles mRNA delivery
ISSN:	1616-301X, 1616-3028
Online Access:	Get full text
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