Polygenic Risk Scores Predict Hypertension Onset and Cardiovascular Risk

Although genetic risk scores have been used to predict hypertension, their utility in the clinical setting remains uncertain. Our study comprised N=218 792 FinnGen participants (mean age 58 years, 56% women) and N=22 624 well-phenotyped FINRISK participants (mean age 50 years, 53% women). We used pu...

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Bibliographic Details
Published in:	Hypertension (Dallas, Tex. 1979) Vol. 77; no. 4; p. 1119
Main Authors:	Vaura, Felix, Kauko, Anni, Suvila, Karri, Havulinna, Aki S, Mars, Nina, Salomaa, Veikko, FinnGen, Cheng, Susan, Niiranen, Teemu
Format:	Journal Article
Language:	English
Published:	United States 01.04.2021
Subjects:	Blood Pressure - physiology Cardiovascular Diseases - epidemiology Cardiovascular Diseases - genetics Cardiovascular Diseases - prevention & control Female Finland - epidemiology Genetic Predisposition to Disease - epidemiology Genome-Wide Association Study - statistics & numerical data Heart Disease Risk Factors Humans Hypertension - epidemiology Hypertension - genetics Hypertension - prevention & control Male Middle Aged Multifactorial Inheritance Patient-Specific Modeling Predictive Value of Tests Preventive Health Services - methods Risk Factors Finland blood pressure association risk factors genetics cardiovascular diseases hypertension
ISSN:	1524-4563, 1524-4563
Online Access:	Get more information
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