Mortality reduction and cost-effectiveness of performing hysterectomy at the time of risk-reducing salpingo-oophorectomy for prophylaxis against serous/serous-like uterine cancers in BRCA1 mutation carriers

To estimate the survival benefit and cost-effectiveness of performing hysterectomy during risk-reducing salpingo-oophorectomy (RRSO) for BRCA1 mutation carriers. Based on a recent prospective cohort study indicating an elevated incidence of serous/serous-like uterine cancers among BRCA1 mutation car...

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Bibliographic Details
Published in:	Gynecologic oncology Vol. 145; no. 3; pp. 549 - 554
Main Authors:	Havrilesky, Laura J., Moss, Haley A., Chino, Junzo, Myers, Evan R., Kauff, Noah D.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.06.2017
Subjects:	Adult Aged BRCA1 Cost-Benefit Analysis Cost-effectiveness Cystadenocarcinoma, Serous - economics Cystadenocarcinoma, Serous - genetics Cystadenocarcinoma, Serous - mortality Cystadenocarcinoma, Serous - prevention & control Female Genes, BRCA1 Germ-Line Mutation Hematology, Oncology and Palliative Medicine Humans Hysterectomy Hysterectomy - economics Hysterectomy - methods Markov Chains Middle Aged Models, Statistical Obstetrics and Gynecology Ovariectomy - economics Ovariectomy - methods Prophylactic Surgical Procedures - economics Prophylactic Surgical Procedures - methods Risk-reducing salpingo-oophorectomy United States - epidemiology Uterine Neoplasms - economics Uterine Neoplasms - genetics Uterine Neoplasms - mortality Uterine Neoplasms - prevention & control Risk-reducing salpingo-oophorectomy Hysterectomy BRCA1 Cost-effectiveness
ISSN:	0090-8258, 1095-6859, 1095-6859
Online Access:	Get full text
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