Histone H3K27ac separates active from poised enhancers and predicts developmental state

Developmental programs are controlled by transcription factors and chromatin regulators, which maintain specific gene expression programs through epigenetic modification of the genome. These regulatory events at enhancers contribute to the specific gene expression programs that determine cell state...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS Jg. 107; H. 50; S. 21931
Hauptverfasser:	Creyghton, Menno P, Cheng, Albert W, Welstead, G Grant, Kooistra, Tristan, Carey, Bryce W, Steine, Eveline J, Hanna, Jacob, Lodato, Michael A, Frampton, Garrett M, Sharp, Phillip A, Boyer, Laurie A, Young, Richard A, Jaenisch, Rudolf
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 14.12.2010
Schlagworte:	Acetylation Animals Cell Differentiation - genetics Cell Line Enhancer Elements, Genetic Gene Expression Regulation, Developmental Histones - genetics Histones - metabolism Mice Mice, Inbred C57BL
ISSN:	1091-6490, 1091-6490
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