Melatonin Augments the Expression of Core Transcription Factors in Aged and Alzheimer’s Patient Skin Fibroblasts

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder. Altered neurogenesis and the appearance of AD pathological hallmarks are fundamental to this disease. SRY-Box transcription factor 2 (Sox2), octamer-binding transcription factor 4 (Oct4), and Nanog are a set of core transcription...

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Veröffentlicht in:	Biology (Basel, Switzerland) Jg. 13; H. 9; S. 698
Hauptverfasser:	Shukla, Mayuri, Duangrat, Raphiporn, Nopparat, Chutikorn, Sotthibundhu, Areechun, Govitrapong, Piyarat
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 01.09.2024
Schlagworte:	adults Advertising executives Aging Alzheimer's disease Cell culture Cell self-renewal Cognitive ability core transcription factors Dementia disorders Disease DNA binding proteins Embryo cells Ethylenediaminetetraacetic acid Fibroblasts Gene regulation Health aspects Human subjects humans Investigations Melatonin Membranes Neurodegeneration Neurodegenerative diseases Neurogenesis Neurons Neuroprotection neuroprotective effect Neurotoxicity Oct-4 protein Oct4 Older people pathogenesis patients Penicillin Pluripotency Proteins Senescence Skin Skin diseases Sox2 Stem cells therapeutics Toxicity Transcription factors United States > US Oct4 Sox2 fibroblasts Alzheimer’s disease Nanog melatonin core transcription factors
ISSN:	2079-7737, 2079-7737
Online-Zugang:	Volltext
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