Loss of Vaccine-Induced Immunity to Varicella over Time

Active surveillance of a sentinel population of 350,000 persons was performed to determine whether the severity and incidence of breakthrough varicella increased with the time since vaccination. The annual rate of breakthrough disease significantly increased with the time since vaccination, from 1.6...

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 356; no. 11; pp. 1121 - 1129
Main Authors:	Chaves, Sandra S, Gargiullo, Paul, Zhang, John X, Civen, Rachel, Guris, Dalya, Mascola, Laurene, Seward, Jane F
Format:	Journal Article
Language:	English
Published:	Boston, MA Massachusetts Medical Society 15.03.2007
Subjects:	Adolescent Adult Age Distribution Age of Onset Biological and medical sciences Chicken pox Chickenpox - epidemiology Chickenpox - immunology Chickenpox - prevention & control Chickenpox Vaccine - administration & dosage Chickenpox Vaccine - immunology Child Child, Preschool General aspects Health maintenance organizations Herpesvirus 3, Human - immunology HMOs Humans Immunization, Secondary Infant Logistic Models Medical sciences Multivariate Analysis Population Surveillance Prevention and actions Public health. Hygiene Public health. Hygiene-occupational medicine Severity of Illness Index Time Factors United States - epidemiology Vaccines United States Infection Medicine Prevention Immunoprophylaxis Skin disease Viral disease Loss Varicella Vaccine Immunity
ISSN:	0028-4793, 1533-4406, 1533-4406
Online Access:	Get full text
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