Regulation of ROS signal transduction by NADPH oxidase 4 localization

Reactive oxygen species (ROS) function as intracellular signaling molecules in a diverse range of biological processes. However, it is unclear how freely diffusible ROS dictate specific cellular responses. In this study, we demonstrate that nicotinamide adenine dinucleotide phosphate reduced oxidase...

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Veröffentlicht in:	The Journal of cell biology Jg. 181; H. 7; S. 1129
Hauptverfasser:	Chen, Kai, Kirber, Michael T, Xiao, Hui, Yang, Yu, Keaney, Jr, John F
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 30.06.2008
Schlagworte:	Animals Antioxidants - pharmacology Cell Proliferation - drug effects Chlorocebus aethiops COS Cells Endoplasmic Reticulum - drug effects Endoplasmic Reticulum - enzymology Endothelial Cells - cytology Endothelial Cells - drug effects Endothelial Cells - enzymology Epidermal Growth Factor - pharmacology ErbB Receptors - metabolism Humans Mice Mutation - genetics NADPH Oxidase 4 NADPH Oxidases - metabolism Oxidation-Reduction - drug effects Phosphorylation - drug effects Protein Transport - drug effects Protein Tyrosine Phosphatase, Non-Receptor Type 1 - metabolism Reactive Oxygen Species - metabolism Signal Transduction - drug effects Substrate Specificity - drug effects
ISSN:	1540-8140, 1540-8140
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