Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression

Phosphatidylinositol-5-phosphate (PtdIns5P) 4-kinase β (PIP4K2B) directly regulates the levels of two important phosphoinositide second messengers, PtdIns5P and phosphatidylinositol-(4,5)-bisphosphate [PtdIns(4,5)P2]. PIP4K2B has been linked to the regulation of gene transcription, to TP53 and AKT a...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Jg. 73; H. 23; S. 6913
Hauptverfasser:	Keune, Willem-Jan, Sims, Andrew H, Jones, David R, Bultsma, Yvette, Lynch, James T, Jirström, Karin, Landberg, Goran, Divecha, Nullin
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.12.2013
Schlagworte:	Breast Neoplasms - diagnosis Breast Neoplasms - genetics Breast Neoplasms - mortality Cadherins - genetics Cadherins - metabolism Carcinoma, Ductal, Breast - diagnosis Carcinoma, Ductal, Breast - genetics Carcinoma, Ductal, Breast - mortality Down-Regulation Female Gene Expression Regulation, Neoplastic - genetics HEK293 Cells Humans MCF-7 Cells Meta-Analysis as Topic Minor Histocompatibility Antigens Phosphotransferases (Alcohol Group Acceptor) - genetics Phosphotransferases (Alcohol Group Acceptor) - metabolism Survival Analysis Tissue Array Analysis - statistics & numerical data Tumor Cells, Cultured
ISSN:	1538-7445, 1538-7445
Online-Zugang:	Weitere Angaben
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