Antimicrobial Peptides: Classification, Design, Application and Research Progress in Multiple Fields

Antimicrobial peptides (AMPs) are a class of small peptides that widely exist in nature and they are an important part of the innate immune system of different organisms. AMPs have a wide range of inhibitory effects against bacteria, fungi, parasites and viruses. The emergence of antibiotic-resistan...

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Bibliographic Details
Published in:Frontiers in microbiology Vol. 11; p. 582779
Main Authors: Huan, Yuchen, Kong, Qing, Mou, Haijin, Yi, Huaxi
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 16.10.2020
Subjects:
antimicrobial peptides
classification
coronavirus
design
Microbiology
mode of action
motifs
application
mode of action
motifs
design
coronavirus
classification
antimicrobial peptides
ISSN:1664-302X, 1664-302X
Online Access:Get full text
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Summary:Antimicrobial peptides (AMPs) are a class of small peptides that widely exist in nature and they are an important part of the innate immune system of different organisms. AMPs have a wide range of inhibitory effects against bacteria, fungi, parasites and viruses. The emergence of antibiotic-resistant microorganisms and the increasing of concerns about the use of antibiotics resulted in the development of AMPs, which have a good application prospect in medicine, food, animal husbandry, agriculture and aquaculture. This review introduces the progress of research on AMPs comprehensively and systematically, including their classification, mechanism of action, design methods, environmental factors affecting their activity, application status, prospects in various fields and problems to be solved. The research progress on antivirus peptides, especially anti-coronavirus (COVID-19) peptides, has been introduced given the COVID-19 pandemic worldwide in 2020.
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Edited by: Giovanna Batoni, University of Pisa, Italy
Reviewed by: Cesar de la Fuente-Nunez, University of Pennsylvania, United States; Paula Gomes, University of Porto, Portugal
This article was submitted to Antimicrobials, Resistance and Chemotherapy, a section of the journal Frontiers in Microbiology
ISSN:1664-302X
1664-302X
DOI:10.3389/fmicb.2020.582779