The chemistry and biological activities of N-acetylcysteine

N-acetylcysteine (NAC) has been in clinical practice for several decades. It has been used as a mucolytic agent and for the treatment of numerous disorders including paracetamol intoxication, doxorubicin cardiotoxicity, ischemia–reperfusion cardiac injury, acute respiratory distress syndrome, bronch...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochimica et biophysica acta Jg. 1830; H. 8; S. 4117 - 4129
Hauptverfasser:	Samuni, Yuval, Goldstein, Sara, Dean, Olivia M., Berk, Michael
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier B.V 01.08.2013
Schlagworte:	acetaminophen acetylcysteine Acetylcysteine - chemistry Acetylcysteine - metabolism Acetylcysteine - pharmacology Animals Antioxidant antioxidant activity Apoptosis - drug effects behavior disorders Blood-Brain Barrier bronchitis Cell Cycle - drug effects Cell Membrane - metabolism cell membranes Cell-permeability cysteine distress Disulfide bond disulfide bonds doxorubicin Glutathione precursor heavy metals Human immunodeficiency virus Humans hydrogen peroxide Mental Disorders - drug therapy N-acetylcysteine nitrogen dioxide poisoning proteins Redox potential signal transduction Signal Transduction - drug effects thiols toxicity NO RS BBB O2 CO3 HNO HOSCN Glutathione precursor TNF INF-γ LPS N-acetylcysteine NO2 NF-κB RNS mTOR OH GSH CD IL N3 RSH IKK SOD Antioxidant I-κB PMN HOCl MMP NAC Disulfide bond ROS Redox potential NAPQI RSOH Ig Cell-permeability ERK
ISSN:	0304-4165, 0006-3002, 1872-8006
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!