HER2/neu Testing in Gastric Cancer by Immunohistochemistry: Assessment of Interlaboratory Variation

Immunohistochemical (IHC) testing for HER2/neu is becoming the standard of care for guiding adjuvant treatment of gastric carcinoma with trastuzumab. To assess interlaboratory variation in IHC staining and interpretation across multiple laboratories. A tissue microarray consisting of 45 cores from 2...

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Bibliographic Details
Published in:	Archives of pathology & laboratory medicine (1976) Vol. 138; no. 11; pp. 1495 - 1502
Main Authors:	Sheffield, Brandon S., Garratt, John, Kalloger, Steve E., Li-Chang, Hector H., Torlakovic, Emina E., Gilks, C. Blake, Schaeffer, David F.
Format:	Journal Article
Language:	English
Published:	United States College of American Pathologists 01.11.2014
Subjects:	Adult Aged Aged, 80 and over Agreements Analysis Antibodies Antibodies, Monoclonal, Humanized - therapeutic use Breast cancer Cancer Cancer therapies Care and treatment Female Gastric cancer Genes, erbB-2 Humans Immunohistochemistry Immunohistochemistry - methods Immunohistochemistry - statistics & numerical data In Situ Hybridization - methods In Situ Hybridization - statistics & numerical data Laboratories Male Medical laboratories Medical tests Metastasis Middle Aged Molecular Targeted Therapy Observer Variation Quality control Receptor, ErbB-2 - antagonists & inhibitors Receptor, ErbB-2 - genetics Receptor, ErbB-2 - metabolism Stomach cancer Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - therapy Tissue Array Analysis - methods Tissue Array Analysis - statistics & numerical data Trastuzumab Tumors Viral antibodies Vancouver British Columbia Canada Canada
ISSN:	0003-9985, 1543-2165, 1543-2165
Online Access:	Get full text
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