Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells

Smooth muscle is a major component of human tissues and is essential for the normal function of a multitude of organs including the intestine, urinary tract and the vascular system. The use of stem cells for cell-based tissue engineering and regeneration strategies represents a promising alternative...

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Bibliographic Details
Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 103; no. 32; p. 12167
Main Authors:	Rodríguez, Larissa V, Alfonso, Zeni, Zhang, Rong, Leung, Joanne, Wu, Benjamin, Ignarro, Louis J
Format:	Journal Article
Language:	English
Published:	United States 08.08.2006
Subjects:	Actins - metabolism Adipose Tissue - cytology Adipose Tissue - metabolism Animals Calcium-Binding Proteins - metabolism Calmodulin-Binding Proteins - metabolism Calponins Cell Differentiation Gene Expression Regulation Humans Microfilament Proteins - metabolism Muscle, Smooth - metabolism Myocytes, Smooth Muscle - cytology Myocytes, Smooth Muscle - metabolism Myosin Heavy Chains - metabolism Rats Rats, Sprague-Dawley
ISSN:	0027-8424
Online Access:	Get more information
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