Surveillance of transmitted HIV-1 drug resistance in Gauteng and KwaZulu-Natal Provinces, South Africa, 2005-2009

Surveillance of human immunodeficiency virus type 1 transmitted drug resistance (TDR) was conducted among pregnant women in South Africa over a 5-year period after the initiation of a large national antiretroviral treatment program. Analysis of TDR data from 9 surveys conducted between 2005 and 2009...

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Vydáno v:Clinical infectious diseases Ročník 54 Suppl 4; s. S334
Hlavní autoři: Hunt, G M, Ledwaba, J, Basson, A E, Moyes, J, Cohen, C, Singh, B, Bertagnolio, S, Jordan, M R, Puren, A, Morris, L
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 15.05.2012
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ISSN:1537-6591, 1537-6591
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Shrnutí:Surveillance of human immunodeficiency virus type 1 transmitted drug resistance (TDR) was conducted among pregnant women in South Africa over a 5-year period after the initiation of a large national antiretroviral treatment program. Analysis of TDR data from 9 surveys conducted between 2005 and 2009 in 2 provinces of South Africa suggests that while TDR remains low (<5%) in Gauteng Province, it may be increasing in KwaZulu-Natal, with the most recent survey showing moderate (5%-15%) levels of resistance to the nonnucleoside reverse transcriptase inhibitor drug class.
Bibliografie:ObjectType-Article-1
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ISSN:1537-6591
1537-6591
DOI:10.1093/cid/cir1017