The epidemiology of hand eczema in the general population - prevalence and main findings

Numerous studies have investigated the prevalence and risk factors of hand eczema in the general population. These studies are of high value as they tend to be less biased than studies using clinical populations and as they are important for healthcare decision makers when they allocate resources. T...

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Vydané v:	Contact dermatitis Ročník 62; číslo 2; s. 75 - 87
Hlavní autori:	Thyssen, Jacob P., Johansen, Jeanne D., Linneberg, Allan, Menné, Torkil
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Oxford, UK Blackwell Publishing Ltd 01.02.2010 Blackwell Wiley Subscription Services, Inc
Predmet:	Adolescent Adult Aged Allergic diseases Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Child Child, Preschool Dermatitis Dermatitis, Allergic Contact - epidemiology Dermatitis, Atopic - epidemiology Dermatitis, Occupational - epidemiology Dermatitis, Occupational - etiology Dermatitis, Occupational - genetics Dermatology Eczema Eczema - epidemiology Eczema - etiology Eczema - genetics Epidemiology Female general population hand dermatitis Hand Dermatoses - epidemiology Hand Dermatoses - etiology Hand Dermatoses - genetics hand eczema Humans Immunopathology Infant Male Medical sciences Metals and various inorganic compounds Middle Aged Nickel - immunology nickel allergy Prevalence public health regulation Risk Factors Sex Factors Skin allergic diseases. Stinging insect allergies Skin involvement in other diseases. Miscellaneous. General aspects Studies Toxicology Young Adult Human Immunopathology Allergy Skin disease Prevalence hand eczema Transition metal general population Dermatitis Epidemiology Hand nickel allergy Eczema Risk factor Predisposition Genetics Nickel Regulation Bibliographic review Public health hand dermatitis
ISSN:	0105-1873, 1600-0536, 1600-0536
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Shrnutí:	Numerous studies have investigated the prevalence and risk factors of hand eczema in the general population. These studies are of high value as they tend to be less biased than studies using clinical populations and as they are important for healthcare decision makers when they allocate resources. This study aimed to review the epidemiology of hand eczema in the general population. Literature was examined using Pubmed‐Medline, Biosis, Science Citation Index, and dermatology text books. On the basis of studies performed between 1964 and 2007, the point prevalence of hand eczema was around 4%, the 1‐year prevalence nearly 10%, whereas the lifetime prevalence reached 15%. Based on seven studies, the median incidence rate of hand eczema was 5.5 cases/1000 person‐years (women = 9.6 and men = 4.0). A high incidence rate was associated with female sex, contact allergy, atopic dermatitis, and wet work. Atopic dermatitis was the single most important risk factor for hand eczema. Hand eczema resulted in medical consultations in 70%, sick leave (> 7 days) in about 20%, and job change in about 10%. Mean sick time was longer among those with allergic hand eczema than those with atopic and irritant hand eczema. Moderate to severe extension of hand eczema was the strongest risk factor for persistence of hand eczema. Other risk factors included early onset of hand eczema and childhood eczema. The aetiology of hand eczema is multifactorial and includes environmental as well as genetic factors. Future studies should focus on unresolved areas of hand eczema, for example, genetic predisposition.
Bibliografia:	istex:622F1B349B49BD77E5AEBFA12CDAC259301E216A The content has not been published previously and is not otherwise submitted for publication. ArticleID:COD1669 ark:/67375/WNG-C2R2K2C2-L ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 14 ObjectType-Article-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23
ISSN:	0105-1873 1600-0536 1600-0536
DOI:	10.1111/j.1600-0536.2009.01669.x