Genetics of dementia: Update and guidelines for the clinician

With increased frequency, clinical geneticists are asked for genetic advice on the heredity of dementia in families. Alzheimer's disease is in most cases a complex disease, but may be autosomal dominant inherited. Mutations in the PSEN1 gene are the most common genetic cause of early onset Alzh...

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Bibliographic Details
Published in:	American journal of medical genetics. Part B, Neuropsychiatric genetics Vol. 159B; no. 6; pp. 628 - 643
Main Authors:	Cohn-Hokke, Petra E., Elting, Mariet W., Pijnenburg, Yolande A.L., van Swieten, John C.
Format:	Journal Article
Language:	English
Published:	Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.09.2012 Wiley-Liss Wiley Subscription Services, Inc
Subjects:	Adult and adolescent clinical studies Age of Onset Algorithms Alzheimer's disease Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dementia - genetics early onset frontotemporal dementia General aspects. Genetic counseling Genetic Association Studies genetic counseling Genetic Predisposition to Disease genetic testing Genetics Humans Medical genetics Medical sciences Neurology Organic mental disorders. Neuropsychology Physicians Practice Guidelines as Topic Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Nervous system diseases Alzheimer disease early onset Recommendation Cerebral disorder Genetic counseling genetic testing Central nervous system disease Genetics Early Degenerative disease Frontotemporal dementia Alzheimer's disease
ISSN:	1552-4841, 1552-485X, 1552-485X
Online Access:	Get full text
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