Platelets and neutrophil extracellular traps collaborate to promote intravascular coagulation during sepsis in mice

Neutrophil extracellular traps (NETs; webs of DNA coated in antimicrobial proteins) are released into the vasculature during sepsis where they contribute to host defense, but also cause tissue damage and organ dysfunction. Various components of NETs have also been implicated as activators of coagula...

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Vydáno v:	Blood Ročník 129; číslo 10; s. 1357
Hlavní autoři:	McDonald, Braedon, Davis, Rachelle P, Kim, Seok-Joo, Tse, Mandy, Esmon, Charles T, Kolaczkowska, Elzbieta, Jenne, Craig N
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 09.03.2017
Témata:	Animals Blood Platelets - immunology Disease Models, Animal Disseminated Intravascular Coagulation - immunology Extracellular Traps - immunology Mice Mice, Inbred C57BL Microscopy, Confocal Sepsis - immunology
ISSN:	1528-0020, 1528-0020
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