Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform

The dynamics and coordination between autophagy machinery and selective receptors during mitophagy are unknown. Also unknown is whether mitophagy depends on pre-existing membranes or is triggered on the surface of damaged mitochondria. Using a ubiquitin-dependent mitophagy inducer, the lactone iverm...

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Bibliographic Details
Published in:	Developmental cell Vol. 50; no. 5; p. 627
Main Authors:	Zachari, Maria, Gudmundsson, Sigurdur R, Li, Ziyue, Manifava, Maria, Cugliandolo, Fiorella, Shah, Ronak, Smith, Matthew, Stronge, James, Karanasios, Eleftherios, Piunti, Caterina, Kishi-Itakura, Chieko, Vihinen, Helena, Jokitalo, Eija, Guan, Jun-Lin, Buss, Folma, Smith, Andrew M, Walker, Simon A, Eskelinen, Eeva-Liisa, Ktistakis, Nicholas T
Format:	Journal Article
Language:	English
Published:	United States 09.09.2019
Subjects:	Animals Apoptosis Regulatory Proteins - metabolism Autophagy-Related Proteins - metabolism Baculoviral IAP Repeat-Containing 3 Protein - metabolism Cells, Cultured Endoplasmic Reticulum - metabolism HEK293 Cells Humans Inhibitor of Apoptosis Proteins - metabolism Mice Mitophagy Mouse Embryonic Stem Cells - metabolism TNF Receptor-Associated Factor 2 - metabolism Ubiquitination mitophagy autophagy autophagosome tomography endoplasmic reticulum super resolution microscopy
ISSN:	1878-1551, 1878-1551
Online Access:	Get more information
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