NMMD: Efficient Cryo-EM Flexible Fitting Based on Simultaneous Normal Mode and Molecular Dynamics atomic displacements

[Display omitted] •NMMD: new method for flexible fitting of atomic structures into cryo-EM maps.•NMMD efficiently combines normal mode analysis and molecular dynamics simulation.•NMMD was tested using synthetic and experimental cryo-EM maps.•Adding normal modes to molecular dynamics makes the fittin...

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