Dietary intake of hexabromocyclododecane diastereoisomers (α-, β-, and γ-HBCD) in the Belgian adult population

► Medium bound estimated daily intake (EDI) of ΣHBCD was 0.99 ng kg −1 bw d −1. ► Diastereoisomer contribution to the EDI was 67% γ-HBCD, 25% α-HBCD and 8% β-HBCD. ► Food groups contributing the most to EDI: meat and the group of “other” products. ► Levels of HBCD were lower than those found in othe...

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Vydáno v:	Chemosphere (Oxford) Ročník 84; číslo 3; s. 279 - 288
Hlavní autoři:	Goscinny, Séverine, Vandevijvere, Stefanie, Maleki, Mehdi, Overmeire, Ilse Van, Windal, Isabelle, Hanot, Vincent, Blaude, Marie-Noelle, Vleminckx, Christiane, Loco, Joris Van
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Kidlington Elsevier Ltd 01.06.2011 Elsevier
Témata:	Adult analysis animal-based foods Applied sciences at-risk population average daily intake Belgium Brominated Flame Retardants (BFRs) diastereomers Diet Diet - statistics & numerical data Dietary intake Environmental Exposure Environmental Exposure - analysis Environmental Exposure - statistics & numerical data Environmental Pollutants Environmental Pollutants - analysis European Union Exact sciences and technology Female Flame Retardants Flame Retardants - analysis Food Analysis Food consumption survey food groups Hexabromocyclododecane (HBCD) Humans Hydrocarbons, Brominated Hydrocarbons, Brominated - analysis Male meat Pollution statistics & numerical data Stereoisomerism Belgium Europe Dietary intake Food consumption survey Hexabromocyclododecane (HBCD) Belgium Brominated Flame Retardants (BFRs) Human Flame retardant Endocrine disruptor Hexabromocyclododecane Carcinogen Survey Adult Bromine Organic compounds Public health Food Chemical contamination
ISSN:	0045-6535, 1879-1298, 1879-1298
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Shrnutí:	► Medium bound estimated daily intake (EDI) of ΣHBCD was 0.99 ng kg −1 bw d −1. ► Diastereoisomer contribution to the EDI was 67% γ-HBCD, 25% α-HBCD and 8% β-HBCD. ► Food groups contributing the most to EDI: meat and the group of “other” products. ► Levels of HBCD were lower than those found in other EU countries. ► The resulting EDI of ΣHBCD was substantially below the proposed thresholds. A study was performed to assess exposure of the Belgian population to HBCD diastereoisomers. Measurements of HBCD were performed by UPLC-MS/MS, on 45 composite samples from 5 major food groups: dairy (products), meat (products), eggs, fish (products) and a group of “other” products. The medium bound estimated average daily intake (EDI) of ΣHBCD in the Belgian population was 0.99 ng kg −1 bw d −1. The diastereoisomer contribution to the mean EDI showed a predominance of γ-HBCD at 67%, followed by α-HBCD at 25% and 8% for β-HBCD. These results are consistent with the pattern found in the two food groups contributing the most to the EDI: meat (products) and the group of “other” products. Anyway, it has to be noted that diastereomeric distribution of HBCD can change due to bioisomerisation in biological material. Levels of HBCD diastereoisomers found in Belgian food samples of animal origin were low in comparison with those found in other EU countries and the resulting EDI was substantially below the proposed thresholds.
Bibliografie:	http://dx.doi.org/10.1016/j.chemosphere.2011.04.048 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0045-6535 1879-1298 1879-1298
DOI:	10.1016/j.chemosphere.2011.04.048