Measles Update — United States, January 1–April 17, 2025
A multistate measles outbreak, predominantly affecting members of close-knit communities with low measles vaccination coverage in New Mexico, Oklahoma, and Texas began in January 2025. As of April 17, a total of 800 cases have been reported in the United States in 2025; 654 (82%) cases in New Mexico...
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| Veröffentlicht in: | MMWR. Morbidity and mortality weekly report Jg. 74; H. 14; S. 232 - 238 |
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| Format: | Journal Article Newsletter |
| Sprache: | Englisch |
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United States
U.S. Government Printing Office
24.04.2025
Centers for Disease Control and Prevention |
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| ISSN: | 0149-2195, 1545-861X, 1545-861X |
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| Abstract | A multistate measles outbreak, predominantly affecting members of close-knit communities with low measles vaccination coverage in New Mexico, Oklahoma, and Texas began in January 2025. As of April 17, a total of 800 cases have been reported in the United States in 2025; 654 (82%) cases in New Mexico, Oklahoma, and Texas have been associated with the ongoing outbreak. These cases represent an approximately 180% increase over the 285 measles cases reported in the United States during all of 2024, and the second highest annual case count in the United States in 25 years. Overall, 771 (96%) patients have been unvaccinated or had unknown vaccination status (77% were unvaccinated, and 14% had unknown vaccination status when excluding 590 cases reported by Texas, which requires explicit consent by law [i.e., opt-in] to enroll in the Texas Immunization Registry), 85 (11%) patients have been hospitalized, and three patients have died. Among 48 (6%) internationally imported cases, 44 (92%) occurred among U.S. residents. Endemic measles was declared eliminated in the United States in 2000 as a direct result of high 2-dose childhood coverage with the measles, mumps, and rubella (MMR) vaccine. However, measles cases and outbreaks continue to occur when travelers with measles return to the United States while they are infectious; larger U.S. outbreaks typically follow importation into close-knit communities with low vaccination coverage. Nationally, risk for widespread measles transmission remains low because of high population-level immunity. To prepare for and prevent measles cases and outbreaks, public health departments should continue working with trusted community messengers on culturally competent community engagement, education, vaccination efforts, and other community infection prevention approaches (e.g., case isolation, contact monitoring, and post-exposure prophylaxis) and coordinating with health care facilities and schools. Increasing national and local MMR vaccination coverage is essential to preventing measles cases and outbreaks. |
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| AbstractList | A multistate measles outbreak, predominantly affecting members of close-knit communities with low measles vaccination coverage in New Mexico, Oklahoma, and Texas began in January 2025. As of April 17, a total of 800 cases have been reported in the United States in 2025; 654 (82%) cases in New Mexico, Oklahoma, and Texas have been associated with the ongoing outbreak. These cases represent an approximately 180% increase over the 285 measles cases reported in the United States during all of 2024, and the second highest annual case count in the United States in 25 years. Overall, 771 (96%) patients have been unvaccinated or had unknown vaccination status (77% were unvaccinated, and 14% had unknown vaccination status when excluding 590 cases reported by Texas, which requires explicit consent by law [i.e., opt-in] to enroll in the Texas Immunization Registry), 85 (11%) patients have been hospitalized, and three patients have died. Among 48 (6%) internationally imported cases, 44 (92%) occurred among U.S. residents. Endemic measles was declared eliminated in the United States in 2000 as a direct result of high 2-dose childhood coverage with the measles, mumps, and rubella (MMR) vaccine. However, measles cases and outbreaks continue to occur when travelers with measles return to the United States while they are infectious; larger U.S. outbreaks typically follow importation into close-knit communities with low vaccination coverage. Nationally, risk for widespread measles transmission remains low because of high population-level immunity. To prepare for and prevent measles cases and outbreaks, public health departments should continue working with trusted community messengers on culturally competent community engagement, education, vaccination efforts, and other community infection prevention approaches (e.g., case isolation, contact monitoring, and post-exposure prophylaxis) and coordinating with health care facilities and schools. Increasing national and local MMR vaccination coverage is essential to preventing measles cases and outbreaks. A multistate measles outbreak, predominantly affecting members of close-knit communities with low measles vaccination coverage in New Mexico, Oklahoma, and Texas began in January 2025. As of April 17, a total of 800 cases have been reported in the United States in 2025; 654 (82%) cases in New Mexico, Oklahoma, and Texas have been associated with the ongoing outbreak. These cases represent an approximately 180% increase over the 285 measles cases reported in the United States during all of 2024, and the second highest annual case count in the United States in 25 years. Overall, 771 (96%) patients have been unvaccinated or had unknown vaccination status (77% were unvaccinated, and 14% had unknown vaccination status when excluding 590 cases reported by Texas, which requires explicit consent by law [i.e., opt-in] to enroll in the Texas Immunization Registry), 85 (11%) patients have been hospitalized, and three patients have died. Among 48 (6%) internationally imported cases, 44 (92%) occurred among U.S. residents. Endemic measles was declared eliminated in the United States in 2000 as a direct result of high 2-dose childhood coverage with the measles, mumps, and rubella (MMR) vaccine. However, measles cases and outbreaks continue to occur when travelers with measles return to the United States while they are infectious; larger U.S. outbreaks typically follow importation into close-knit communities with low vaccination coverage. Nationally, risk for widespread measles transmission remains low because of high population-level immunity. To prepare for and prevent measles cases and outbreaks, public health departments should continue working with trusted community messengers on culturally competent community engagement, education, vaccination efforts, and other community infection prevention approaches (e.g., case isolation, contact monitoring, and post-exposure prophylaxis) and coordinating with health care facilities and schools. Increasing national and local MMR vaccination coverage is essential to preventing measles cases and outbreaks.A multistate measles outbreak, predominantly affecting members of close-knit communities with low measles vaccination coverage in New Mexico, Oklahoma, and Texas began in January 2025. As of April 17, a total of 800 cases have been reported in the United States in 2025; 654 (82%) cases in New Mexico, Oklahoma, and Texas have been associated with the ongoing outbreak. These cases represent an approximately 180% increase over the 285 measles cases reported in the United States during all of 2024, and the second highest annual case count in the United States in 25 years. Overall, 771 (96%) patients have been unvaccinated or had unknown vaccination status (77% were unvaccinated, and 14% had unknown vaccination status when excluding 590 cases reported by Texas, which requires explicit consent by law [i.e., opt-in] to enroll in the Texas Immunization Registry), 85 (11%) patients have been hospitalized, and three patients have died. Among 48 (6%) internationally imported cases, 44 (92%) occurred among U.S. residents. Endemic measles was declared eliminated in the United States in 2000 as a direct result of high 2-dose childhood coverage with the measles, mumps, and rubella (MMR) vaccine. However, measles cases and outbreaks continue to occur when travelers with measles return to the United States while they are infectious; larger U.S. outbreaks typically follow importation into close-knit communities with low vaccination coverage. Nationally, risk for widespread measles transmission remains low because of high population-level immunity. To prepare for and prevent measles cases and outbreaks, public health departments should continue working with trusted community messengers on culturally competent community engagement, education, vaccination efforts, and other community infection prevention approaches (e.g., case isolation, contact monitoring, and post-exposure prophylaxis) and coordinating with health care facilities and schools. Increasing national and local MMR vaccination coverage is essential to preventing measles cases and outbreaks. |
| Audience | Professional |
| Author | Chatham-Stephens, Kevin Raines, Kelley Daskalakis, Demetre C. Leung, Jessica Patel, Manisha Sugerman, David Martinez, Diana Shetty, Varun Filardo, Thomas D. Rai, Saroj Rota, Paul A. Holzinger, Nora Mathis, Adria D. Stanislawski, Emma Wiley, Nicole |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/40273019$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1126/science.aaa3662 10.15585/mmwr.mm7345a4 10.1093/cid/ciae470 10.1016/S0140-6736(24)00850-X 10.15585/mmwr.mm7341a3 |
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| References_xml | – volume: 348 start-page: 694 year: 2015 ident: key-10.15585/mmwr.mm7414a1-202504240824-R3 article-title: Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality. publication-title: Science doi: 10.1126/science.aaa3662 – ident: key-10.15585/mmwr.mm7414a1-202504240824-R8 – volume: 73 start-page: 1036 year: 2024 ident: key-10.15585/mmwr.mm7414a1-202504240824-R5 article-title: Progress toward measles elimination—worldwide, 2000–2023. publication-title: MMWR Morb Mortal Wkly Rep doi: 10.15585/mmwr.mm7345a4 – ident: key-10.15585/mmwr.mm7414a1-202504240824-R10 – volume: 80 start-page: 663 year: 2025 ident: key-10.15585/mmwr.mm7414a1-202504240824-R1 article-title: The effects of vaccination status and age on clinical characteristics and severity of measles cases in the United States in the postelimination era, 2001–2022. publication-title: Clin Infect Dis doi: 10.1093/cid/ciae470 – volume: 62 start-page: 1 year: 2013 ident: key-10.15585/mmwr.mm7414a1-202504240824-R4 article-title: Prevention of measles, rubella, congenital rubella syndrome, and mumps, 2013: summary recommendations of the Advisory Committee on Immunization Practices (ACIP). publication-title: MMWR Recomm Rep – volume: 403 start-page: 2307 year: 2024 ident: key-10.15585/mmwr.mm7414a1-202504240824-R2 article-title: Contribution of vaccination to improved survival and health: modelling 50 years of the Expanded Programme on Immunization. publication-title: Lancet doi: 10.1016/S0140-6736(24)00850-X – volume: 73 start-page: 925 year: 2024 ident: key-10.15585/mmwr.mm7414a1-202504240824-R9 article-title: Coverage with selected vaccines and exemption rates among children in kindergarten—United States, 2023–24 school year. publication-title: MMWR Morb Mortal Wkly Rep doi: 10.15585/mmwr.mm7341a3 – ident: key-10.15585/mmwr.mm7414a1-202504240824-R6 – volume: 97 start-page: 485 year: 2022 ident: key-10.15585/mmwr.mm7414a1-202504240824-R7 article-title: Update: circulation of active genotypes of measles virus and recommendations for use of sequence analysis to monitor viral transmission. publication-title: Wkly Epidemiol Rec |
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| SubjectTerms | Adolescent Adult Child Child, Preschool Disease Outbreaks - prevention & control Female Full Report Health aspects Humans Infant Male Measles Measles - epidemiology Measles - prevention & control Measles Vaccine - administration & dosage Measles-mumps-rubella vaccine Measles-Mumps-Rubella Vaccine - administration & dosage Population Surveillance Prevention Public health Travelers United States - epidemiology Vaccination Vaccination - statistics & numerical data Vaccination Coverage - statistics & numerical data Young Adult |
| Title | Measles Update — United States, January 1–April 17, 2025 |
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