Redefinition of the human mast cell transcriptome by deep-CAGE sequencing

Mast cells (MCs) mature exclusively in peripheral tissues, hampering research into their developmental and functional programs. Here, we employed deep cap analysis of gene expression on skin-derived MCs to generate the most comprehensive view of the human MC transcriptome ever reported. An advantage...

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Bibliographic Details
Published in:	Blood Vol. 123; no. 17; p. e58
Main Authors:	Motakis, Efthymios, Guhl, Sven, Ishizu, Yuri, Itoh, Masayoshi, Kawaji, Hideya, de Hoon, Michiel, Lassmann, Timo, Carninci, Piero, Hayashizaki, Yoshihide, Zuberbier, Torsten, Forrest, Alistair R R, Babina, Magda
Format:	Journal Article
Language:	English
Published:	United States 24.04.2014
Subjects:	Amino Acid Motifs Bone Morphogenetic Proteins - metabolism Cell Differentiation Cell Lineage Cluster Analysis Databases, Factual Genetic Markers Hematopoiesis - genetics Hematopoietic Stem Cells - cytology High-Throughput Nucleotide Sequencing - methods Humans Immune System Mast Cells - cytology Multigene Family Promoter Regions, Genetic Sequence Analysis, DNA - methods Skin - metabolism Transcriptome
ISSN:	1528-0020, 1528-0020
Online Access:	Get more information
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