Tumor necrosis factor reduces Plasmodium falciparum growth and activates calcium signaling in human malaria parasites

Plasmodium has a complex biology including the ability to interact with host signals modulating their function through cellular machinery. Tumor necrosis factor (TNF) elicits diverse cellular responses including effects in malarial pathology and increased infected erythrocyte cytoadherence. As TNF l...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochimica et biophysica acta Jg. 1860; H. 7; S. 1489 - 1497
Hauptverfasser:	Cruz, Laura N., Wu, Yang, Ulrich, Henning, Craig, Alister G., Garcia, Célia R.S.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier B.V 01.07.2016
Schlagworte:	agglutinins agonists antigens Antimalarials - pharmacology calcium Calcium signaling Calcium Signaling - drug effects cell adhesion Cell Adhesion - drug effects cell proliferation Cells, Cultured confocal microscopy cyclic AMP Cytoadhesion Dose-Response Relationship, Drug Endothelial Cells - drug effects Endothelial Cells - metabolism Endothelial Cells - parasitology erythrocytes Erythrocytes - parasitology ethylene glycol tetraacetic acid genes Host-Parasite Interactions Humans Malaria parasitemia parasites Plasmodium falciparum Plasmodium falciparum - drug effects Plasmodium falciparum - growth & development Plasmodium falciparum - immunology Plasmodium falciparum - metabolism Proliferating Cell Nuclear Antigen - metabolism Proliferating cell nuclear antigen-1 Protozoan Proteins - metabolism quantitative polymerase chain reaction sodium Time Factors Tumor necrosis factor Tumor Necrosis Factor-alpha - pharmacology tumor necrosis factors wheat germ Calcium signaling Proliferating cell nuclear antigen-1 Plasmodium falciparum Malaria Tumor necrosis factor Cytoadhesion
ISSN:	0304-4165, 0006-3002, 1872-8006
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!