LDL-cholesterol signaling induces breast cancer proliferation and invasion

Lipids and cholesterol in particular, have long been associated with breast cancer (BC) onset and progression. However, the causative effects of elevated lipid levels and breast cancer remain largely undisclosed and were the subject of the present study. We took advantage of well-established in vitr...

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Bibliographic Details
Published in:	Lipids in health and disease Vol. 13; no. 1; p. 16
Main Authors:	Rodrigues dos Santos, Catarina, Domingues, Germana, Matias, Inês, Matos, João, Fonseca, Isabel, de Almeida, José Mendes, Dias, Sérgio
Format:	Journal Article
Language:	English
Published:	London BioMed Central 15.01.2014 BioMed Central Ltd Springer Nature B.V
Subjects:	Analysis Animals Biomedical and Life Sciences Breast cancer Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell Adhesion Cell adhesion & migration Cell growth Cell Line, Tumor Cell Movement Cell Proliferation Cholesterol Cholesterol, LDL - physiology Clinical Nutrition Development and progression Diet, High-Fat - adverse effects Disease prevention Female Gene Expression Gene Expression Regulation, Neoplastic Genotype & phenotype Health aspects Humans Hypercholesterolemia Life Sciences Lipidology Lipids Lung Neoplasms - metabolism Lung Neoplasms - secondary Medical Biochemistry Mice Mice, Inbred BALB C Mice, SCID Neoplasm Invasiveness Neoplasm Transplantation Pathology Protein Processing, Post-Translational Signal Transduction Software Statins Studies Tumor Burden Tumors Tumor growth LDL-cholesterol Breast cancer
ISSN:	1476-511X, 1476-511X
Online Access:	Get full text
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